IDIOPATIK TROMBOSITOPENIA PURPURA ADALAH PDF

Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Idiopathic thrombocytopenic purpura (ITP) or immune thrombocytopenic purpura is a disease .. Purwanto I. Purpura trombositopenia idiopatik. In: Sudoyo AW. Idiopathic thrombocytopenic purpura (ITP) or immune thrombocytopenic purpura is a disease Purwanto I. Purpura trombositopenia idiopatik.

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In adults, it is more often a long-term chronic disease and can occur pufpura a viral infection, with use of certain drugs, during pregnancy, or as part of an immune disorder.

Immune thrombocytopenic purpura – Wikipedia

Psaila B, Bussel T. Children should be discouraged from rough contact sports or other activities that increase the risk of trauma.

Thrombopoietin TPO receptor agonists including eltrombopag and romiplostim have offered an important new option iidiopatik treating ITP.

The latter examination in ITP shows low numbers of normal-sized platelets, occasionally also giant platelets, while erythrocytes and leukocytes have a normal morphology. Accessed Juni 10, Abstract Idiopathic thrombocytopenic purpura ITP is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause.

N Engl J Med. Care, Recommendations, and Protecting Practitioners. Platelet transfusion is not normally recommended and is usually unsuccessful in raising a patient’s platelet count. Thrombopoietin receptor agonists are pharmaceutical agents that stimulate platelet production in the bone marrow. Then, secondary causes 5—10 percent of suspected ITP cases should be excluded. Br J Haematol ; Recommendations of the American Society of Hematology.

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In adults, particularly those living in areas with a high prevalence of Helicobacter pylori which normally inhabits the stomach wall and has been associated with peptic ulcersidentification and treatment of this infection has been shown to improve platelet counts in a third of patients.

This website also contains material copyrighted by 3rd parties. Discussion There is marked variability in the clinical presentation of ITP.

Idiopathic thrombocytopenic purpura

Less common are epistaxis, gingival bleeding, and menorrhagia. The epidemiology of immune thrombocytopenic purpura. At least 70 percent of childhood cases will end up in remission within six months, even without treatment.

Please review our privacy policy. ITP symptoms can include any of the following: In mild cases, only careful observation may be required but very low counts or significant bleeding may prompt treatment with corticosteroidsintravenous immunoglobulinanti-D immunoglobulinor immunosuppressive medications.

ITP affects women more often than men. Hypersensitivity and autoimmune diseases Nevertheless, in the case of an ITP patient already scheduled for surgery who has a dangerously low platelet count and has experienced a poor response to other treatments, IVIg can rapidly increase platelet counts, and can also help reduce the risk of major bleeding by transiently increasing platelet counts.

Support Center Support Center. Graves’ disease Myasthenia gravis Pernicious anemia.

In children, the disease usually goes away without treatment. No significant difference was noted in the rate of survival between males and females. When to Contact a Medical Professional. Purpuda mortality rate due to chronic ITP varies but tends to be higher relative to the general population for any age range.

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Signs of chronic disease, infection, wasting, or poor nutrition indicate that the patient has another illness. The initial treatment of ITP includes: Semple JW, Freedman J. The Netherlands Journal of Medicine.

Many older recommendations suggested a certain platelet count threshold usually somewhere below Idiopathic thrombocytopenic purpura ITP is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause.

Cellular immune mechanisms in autoimmune thrombocytopenic purpura: Adults are usually started on a steroid medicine called prednisone. Buku Ajar Ilmu Penyakit Dalam.

A bone purpkra aspiration or biopsy may also be done. Red Blanchable Erythema Generalized drug eruptions viral exanthems toxic erythema systemic lupus erythematosus. Nil Conflict of Interest: Dapsone also called diphenylsulfone, DDS, or avlosulfon is an anti-infective sulfone drug.

Refractory ITP not responsive to conventional treatment may require splenectomythe surgical removal of the spleen. The procedure is potentially risky in ITP cases due to the increased possibility of significant bleeding during surgery.

Other biochemical examinations, liver function tests, and ultrasonography of iviopatik were normal.